Around 110ha of parkland, largely contaminated former industrial land, will be landscaped to create the Olympic Park. Organisers said more than £200 million has been allocated for the work.
The area will be home to the Olympic Stadium, Aquatics Centre, Velopark, multi-sports arena and Eton Manor outdoor sports complex.
The scheme was designed by LDA Design and Hargreaves Associates with the Olympic Delivery Authority (ODA) and the London Development Agency, which is creating the legacy masterplan framework. At peak times in 2012, up to 130,000 spectators are expected at the park.
ODA chief executive David Higgins said: "It will be a park for the 21st century, setting high standards combining the best of British park heritage with sustainable living. It will be a fantastic backdrop for the games and the heart of the new community post-2012."
The London 2012 Gardens, a "mini Kew", will link the Aquatics Centre and the Olympic Stadium. It will feature 2,000 trees, 250 species of plants, 2.9km of rivers and 102ha of open land.
The southern part of the park will focus on providing riverside gardens, markets, events, cafes and bars. The northern area will be a quieter public space.
Hargreaves Associates founder and design director George Hargreaves said: "We have created two distinct parks for the East End through reclamation."