The RENEW Northwest employment study calls for measures such as section 106 deals to be used to help local people access jobs on developments in their area.
It adds that ethnic minorities and women are under-represented on regeneration boards while jobs created by new developments favour highly-skilled workers.
Gender impact should be routinely assessed in scheme proposals and equality must be taken into account when all regeneration programmes are considered, it argues.
The report draws on work by Oxfam and Sheffield Hallam University as well as the agency's own research.
From Getting By to Getting On is available at PlanningResource.co.uk/doc.