Gleeson Homes drew up the housing proposal as part of the second phase of development in Beswick. The scheme will include eight courtyards and some shops.
Manchester City Council has meanwhile prepared plans for an academy specialising in the built environment. It could feature a community sports hall and a library with adult education facilities. Subject to approval, work could start next September, with the building opening in 2010.
New East Manchester chief executive Tom Russell said: "The objective is to provide a sustainable neighbourhood that will offer a good quality of life. These developments will create housing and education facilities that serve Beswick's growing population."