According to a statement from the Ministry of Housing, Communities and Local Government (MHCLG), Pocklington has taken over from Dame Melanie Dawes as the department's permanent secretary.
His appointment, which starts immediately, follows approval from the cabinet secretary and the Prime Minister, the MHLCG said. It added that Dawes left the civil service in February and Pocklington has been acting in her role since.
Before February, Pocklington was the ministry's director general for housing and building safety.
As permanent secretary, he will oversee the MHCLG's decentralisation and local growth division, led by director general Simon Ridley.
The ministry's planning functions sit within this division, led by planning director Simon Gallagher.
Pocklington said: "It’s an honour to be leading the department as we respond to the nation’s current challenges and support those who need our help most.
"MHCLG has a critically important agenda to level up all parts of our country, support local government and deliver the homes the country needs.
"I look forward to building on the department’s welcoming and inclusive culture and working closely with all our stakeholders to deliver for the government and the public."
Housing secretary, Robert Jenrick, said: "Jeremy is a highly talented and dedicated senior civil servant who has been a great support to me since I became secretary of state and most recently as we work intensively to respond to Covid."
Dawes was appointed permanent secretary at the then Department for Communities and Local Government in 2015, taking over from Lord Kerslake.