Johnson launched the City in the East framework, detailing how development could take place from London Bridge to Dartford and Ilford, yesterday.
The masterplan – which will act as part of planning guidance for local boroughs – brings together a number of so-called opportunity areas, as well as showing where future infrastructure may encourage development.
The blueprint includes proposals for:
30,000 homes on the Isle of Dogs
21,500 homes in Bexley and Thamesmead
5,000 homes in Ilford
1,900 homes at London Bridge
Johnson said: "East London is already enjoying incredible growth and the City in the East plans reflect how we make the area an even better place to live and work over the next 20 years.
"This blueprint reflects identified areas of land in London to build on and it will allow us to co-ordinate not only housing and commercial developments, but significant transport infrastructure to ensure this part of the capital can continue to flourish with hundreds of thousands of new jobs that will help the capital to remain the best big city in the world."
He added that the timing was perfect for the document.
"The majority of borough plan core strategies are about to be reviewed, the London Plan review will commence post May 2016 and Transport for London’s plans are progressing at pace," said Johnson.
"There is developer interest, there are significant public land holdings being brought forward for delivery and there is strong local and strategic leadership to deliver the long heralded City in the East."
Images of the masterplan proposals can be found here.