The hybrid planning application seeks detailed planning permission for the first three phases of the Neptune Wharf scheme - including 600 of the new homes - and outline permission for the final fourth phase, which includes the final 200 homes and the school.
According to Neptune, recently adopted Greater London Authority and London Borough of Tower Hamlets planning strategies for the area will see it "change from a worn out industrial zone to an exciting new mixed-use urban quarter that builds upon existing characteristics such as local cultural industry clusters, a number of new waterways and the close proximity to the wider Legacy schemes".
Patrick Heffron, director of Neptune Group, said: "As a company we committed to Fish Island well ahead of the 2005 Olympic announcement and we are delighted that after several years of detailed discussions with the various planning agencies, we now have a policy platform and agreed framework under which the Neptune Wharf scheme can come forward."
"Our proposals provide significant new homes and new employment space, as well as infrastructure to support the wider regeneration of the area. We now expect to see many more privately driven proposals come forward in this exciting Olympic fringe area."
Neptune said it hopes that the scheme will receive planning permission early in 2013.